TradionP: Prototype Expert System for personalized cancer treatment and diagnosis for cancer patients.

Project Description

The objective of this project is to create a new standard for comprehensive management of cancer patients in order to guide multimodal therapy (surgery, radiotherapy and chemotherapy), in a personalized and effective manner.

The achievement of this objective is technically addressed by creating a multimodal database that contains information from the oncology patient’s information (clinical, histopathological data, medical imaging and molecular profiling).

The expert system is being created in along 3 different deliverables within the project:

• Multimodal Database that contains information (clinical, histopathological, and molecular profiles of medical data image) of studied cases and controls, this is, 1,000 patients (500 treated with targeted therapies, and 500 not treated with these therapies) with advanced breast, lung and colorectal cancer, among others.
• Software application to insert, modify, view and extract information from personalized treatment from data collected in the database.
• Predictive algorithms to design individualized treatments, optimal for managing patients with advanced cancer, depending on the tumor phenotype obtained by integrating data of different nature (Diagnostic tests)

Collaborating Companies or Organisations

Indra's Role

Indra is the Project Coordinator; in addition, Indra will integrate and deploy the entire program. Within these deliverables, Indra provides modeling, development, implementation and infrastructure of the multimodal database application and the development framework for the acquisition and processing of the information as well as and integration of all deliverables described in a demonstrable prototype.

Universities and Technological Centres

Outsourcing:

Technologies used

• Oracle RDBMS
• Oracle APEX (Pl/Sql)
• VMWare Virtualization
• Development of the SVM & DLDA algorithms in Java applying open source libraries produced by the Weka Project

More information

This Integrated Project has been funded by the CDTI through the ERDF: European Regional Development Fund (2007-13)